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SMILES: CCC(C1CC1)n1c(CC)nc2c(nccc12)-c1ccc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=JYDUPUKAOKKYHE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220496   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1/2


(Rattus norvegicus (rat)-RAT)		BDBM50220496
PNG
(CHEMBL24803)
Show SMILES CCC(C1CC1)n1c(CC)nc2c(nccc12)-c1ccc(cc1Cl)C(F)(F)F
Show InChI InChI=1S/C21H21ClF3N3/c1-3-16(12-5-6-12)28-17-9-10-26-19(20(17)27-18(28)4-2)14-8-7-13(11-15(14)22)21(23,24)25/h7-12,16H,3-6H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars
PubMed
 2.90n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 129-31 (2003)


BindingDB Entry DOI: 10.7270/Q2DZ0BGD
More data for this
Ligand-Target Pair