BDBM50220819 CHEMBL58487

SMILES: ONC(=O)CCCCCCNC(=O)c1cc2cc(F)ccc2[nH]1

InChI Key: InChIKey=QFDZOAYXIFXZGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (HDAC1 and HDAC2) (Homo sapiens (Human))	BDBM50220819 (CHEMBL58487) Show SMILES ONC(=O)CCCCCCNC(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C16H20FN3O3/c17-12-6-7-13-11(9-12)10-14(19-13)16(22)18-8-4-2-1-3-5-15(21)20-23/h6-7,9-10,19,23H,1-5,8H2,(H,18,22)(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity was tested against histone deacetylase (HDAC).				Bioorg Med Chem Lett 13: 1897-901 (2003) BindingDB Entry DOI: 10.7270/Q2NC63D6
					More data for this Ligand-Target Pair