BDBM50220844 5-(5-cyclopropyl-4-fluoro-1H-pyrazol-3-yl)-1H-tetrazole::CHEMBL236728

SMILES: Fc1c(n[nH]c1C1CC1)-c1nnn[nH]1

InChI Key: InChIKey=IALMENDAOFEPFH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50220844 (5-(5-cyclopropyl-4-fluoro-1H-pyrazol-3-yl)-1H-tetr...) Show SMILES Fc1c(n[nH]c1C1CC1)-c1nnn[nH]1 Show InChI InChI=1S/C7H7FN6/c8-4-5(3-1-2-3)9-10-6(4)7-11-13-14-12-7/h3H,1-2H2,(H,9,10)(H,11,12,13,14)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50220844 (5-(5-cyclopropyl-4-fluoro-1H-pyrazol-3-yl)-1H-tetr...) Show SMILES Fc1c(n[nH]c1C1CC1)-c1nnn[nH]1 Show InChI InChI=1S/C7H7FN6/c8-4-5(3-1-2-3)9-10-6(4)7-11-13-14-12-7/h3H,1-2H2,(H,9,10)(H,11,12,13,14)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair