BDBM50220977 CHEMBL68547

SMILES: [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2N

InChI Key: InChIKey=JHOKRRBMPVAKAN-WGMWDUQUSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50220977 (CHEMBL68547) Show SMILES [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2N Show InChI InChI=1S/C22H30N4/c23-21-17-13-26(14-18(17)21)12-6-11-24-22-15-7-2-1-3-9-19(15)25-20-10-5-4-8-16(20)22/h4-5,8,10,17-18,21H,1-3,6-7,9,11-14,23H2,(H,24,25)/t17-,18+,21+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards cloned human H3L receptor				Bioorg Med Chem Lett 13: 2131-5 (2003) BindingDB Entry DOI: 10.7270/Q2K073N9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50220977 (CHEMBL68547) Show SMILES [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2N Show InChI InChI=1S/C22H30N4/c23-21-17-13-26(14-18(17)21)12-6-11-24-22-15-7-2-1-3-9-19(15)25-20-10-5-4-8-16(20)22/h4-5,8,10,17-18,21H,1-3,6-7,9,11-14,23H2,(H,24,25)/t17-,18+,21+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards rat cortical Histamine H3 receptor				Bioorg Med Chem Lett 13: 2131-5 (2003) BindingDB Entry DOI: 10.7270/Q2K073N9
					More data for this Ligand-Target Pair