BDBM50221082 (3R,4S)-1-(6-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)-4-(2,4,5-trifluorophenyl)pyrrolidin-3-amine::CHEMBL236084

SMILES: N[C@H]1CN(C[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=FPTQROWVJQTCIK-KDOFPFPSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50221082 ((3R,4S)-1-(6-(3-(trifluoromethyl)phenyl)pyrimidin-...) Show SMILES N[C@H]1CN(C[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H16F6N4/c22-15-6-17(24)16(23)5-13(15)14-8-31(9-18(14)28)20-7-19(29-10-30-20)11-2-1-3-12(4-11)21(25,26)27/h1-7,10,14,18H,8-9,28H2/t14-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4				Bioorg Med Chem Lett 17: 5638-42 (2007) Article DOI: 10.1016/j.bmcl.2007.07.081 BindingDB Entry DOI: 10.7270/Q2319WRX
					More data for this Ligand-Target Pair