BDBM50221150 8a-benzyl-2-(4-methoxyphenylsulfonyl)-1,2,3,4,8,8a-hexahydroisoquinolin-6(7H)-one::CHEMBL247599

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccccc2)C1

InChI Key: InChIKey=BYNLAHCUPZMLFH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221150 (8a-benzyl-2-(4-methoxyphenylsulfonyl)-1,2,3,4,8,8a...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccccc2)C1 |t:15| Show InChI InChI=1S/C23H25NO4S/c1-28-21-7-9-22(10-8-21)29(26,27)24-14-12-19-15-20(25)11-13-23(19,17-24)16-18-5-3-2-4-6-18/h2-10,15H,11-14,16-17H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair