BDBM50221169 8a-benzyl-2-(phenylsulfonyl)-1,2,3,4,8,8a-hexahydroisoquinolin-6(7H)-one::CHEMBL393061

SMILES: O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=MLKHMNLURPWDME-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221169 (8a-benzyl-2-(phenylsulfonyl)-1,2,3,4,8,8a-hexahydr...) Show SMILES O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccccc1 |c:18| Show InChI InChI=1S/C22H23NO3S/c24-20-11-13-22(16-18-7-3-1-4-8-18)17-23(14-12-19(22)15-20)27(25,26)21-9-5-2-6-10-21/h1-10,15H,11-14,16-17H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair