BDBM50221176 8a-(4-nitrobenzyl)-2-(4-tert-butylphenylsulfonyl)-1,2,3,4,8,8a-hexahydroisoquinolin-6(7H)-one::CHEMBL247634
SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccc(cc2)[N+]([O-])=O)C1
InChI Key: InChIKey=MEZKIIXLYYRZES-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50221176 (8a-(4-nitrobenzyl)-2-(4-tert-butylphenylsulfonyl)-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corcept Therapeutics Curated by ChEMBL | Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus | Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B | |||||||||||
More data for this Ligand-Target Pair |