BDBM50221180 8a-(4-fluorobenzyl)-2-(4-tert-butylphenylsulfonyl)-1,2,3,4,8,8a-hexahydroisoquinolin-6(7H)-one::CHEMBL400161

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccc(F)cc2)C1

InChI Key: InChIKey=DKEARPPUMVSQLZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221180 (8a-(4-fluorobenzyl)-2-(4-tert-butylphenylsulfonyl)...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccc(F)cc2)C1 |t:17| Show InChI InChI=1S/C26H30FNO3S/c1-25(2,3)20-6-10-24(11-7-20)32(30,31)28-15-13-21-16-23(29)12-14-26(21,18-28)17-19-4-8-22(27)9-5-19/h4-11,16H,12-15,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221180 (8a-(4-fluorobenzyl)-2-(4-tert-butylphenylsulfonyl)...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccc(F)cc2)C1 |t:17| Show InChI InChI=1S/C26H30FNO3S/c1-25(2,3)20-6-10-24(11-7-20)32(30,31)28-15-13-21-16-23(29)12-14-26(21,18-28)17-19-4-8-22(27)9-5-19/h4-11,16H,12-15,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor in SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression by MMTV5 r...				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair