BDBM50221189 2-(8a-benzyl-6-oxo-3,4,6,7,8,8a-hexahydroisoquinolin-2(1H)-ylsulfonyl)benzonitrile::CHEMBL391182

SMILES: O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccccc1C#N

InChI Key: InChIKey=TWVFKAUSUVXHPA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221189 (2-(8a-benzyl-6-oxo-3,4,6,7,8,8a-hexahydroisoquinol...) Show SMILES O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccccc1C#N |c:18| Show InChI InChI=1S/C23H22N2O3S/c24-16-19-8-4-5-9-22(19)29(27,28)25-13-11-20-14-21(26)10-12-23(20,17-25)15-18-6-2-1-3-7-18/h1-9,14H,10-13,15,17H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair