BDBM50221194 8a-benzyl-2-(4-phenoxyphenylsulfonyl)-1,2,3,4,8,8a-hexahydroisoquinolin-6(7H)-one::CHEMBL247601
SMILES: O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccc(Oc2ccccc2)cc1
InChI Key: InChIKey=PIIFFMFVGAJRHY-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50221194 (8a-benzyl-2-(4-phenoxyphenylsulfonyl)-1,2,3,4,8,8a...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 163 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corcept Therapeutics Curated by ChEMBL | Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus | Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B | |||||||||||
More data for this Ligand-Target Pair |