BDBM50221195 8a-benzyl-2-(biphenyl-4-sulfonyl)-1,3,4,7,8,8a-hexahydro-2H-isoquinolin-6-one::CHEMBL247235

SMILES: O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=ULSWLLCHBONCEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221195 (8a-benzyl-2-(biphenyl-4-sulfonyl)-1,3,4,7,8,8a-hex...) Show SMILES O=C1CCC2(Cc3ccccc3)CN(CCC2=C1)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |c:18| Show InChI InChI=1S/C28H27NO3S/c30-26-15-17-28(20-22-7-3-1-4-8-22)21-29(18-16-25(28)19-26)33(31,32)27-13-11-24(12-14-27)23-9-5-2-6-10-23/h1-14,19H,15-18,20-21H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair