BDBM50221343 4-(2-(2-fluorophenyl)-4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridine::CHEMBL236298

SMILES: COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1F

InChI Key: InChIKey=AYGBSYHQULAMPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50221343 (4-(2-(2-fluorophenyl)-4-(6-methoxynaphthalen-2-yl)...) Show SMILES COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1F Show InChI InChI=1S/C25H18FN3O/c1-30-20-9-8-17-14-19(7-6-18(17)15-20)24-23(16-10-12-27-13-11-16)28-25(29-24)21-4-2-3-5-22(21)26/h2-15H,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 17: 5514-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.052 BindingDB Entry DOI: 10.7270/Q2542N96
					More data for this Ligand-Target Pair