BDBM50221349 4-(2-(2-chloro-4-(methylsulfinyl)phenyl)-4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridine::CHEMBL236924

SMILES: COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(cc1Cl)S(C)=O

InChI Key: InChIKey=WTIQLLRDBWUMJC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50221349 (4-(2-(2-chloro-4-(methylsulfinyl)phenyl)-4-(6-meth...) Show SMILES COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(cc1Cl)S(C)=O Show InChI InChI=1S/C26H20ClN3O2S/c1-32-20-6-5-17-13-19(4-3-18(17)14-20)25-24(16-9-11-28-12-10-16)29-26(30-25)22-8-7-21(33(2)31)15-23(22)27/h3-15H,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 17: 5514-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.052 BindingDB Entry DOI: 10.7270/Q2542N96
					More data for this Ligand-Target Pair