BDBM50221351 4-(2-(2-ethylphenyl)-4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridine::CHEMBL236504

SMILES: CCc1ccccc1-c1nc(c([nH]1)-c1ccc2cc(OC)ccc2c1)-c1ccncc1

InChI Key: InChIKey=QKXNRULCABHVDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50221351 (4-(2-(2-ethylphenyl)-4-(6-methoxynaphthalen-2-yl)-...) Show SMILES CCc1ccccc1-c1nc(c([nH]1)-c1ccc2cc(OC)ccc2c1)-c1ccncc1 Show InChI InChI=1S/C27H23N3O/c1-3-18-6-4-5-7-24(18)27-29-25(19-12-14-28-15-13-19)26(30-27)22-9-8-21-17-23(31-2)11-10-20(21)16-22/h4-17H,3H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	346	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 17: 5514-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.052 BindingDB Entry DOI: 10.7270/Q2542N96
					More data for this Ligand-Target Pair