BDBM50221356 4-(2-(2,6-dichlorophenyl)-4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridine::CHEMBL236503

SMILES: COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1c(Cl)cccc1Cl

InChI Key: InChIKey=VMNHHXKKCJDTHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50221356 (4-(2-(2,6-dichlorophenyl)-4-(6-methoxynaphthalen-2...) Show SMILES COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1c(Cl)cccc1Cl Show InChI InChI=1S/C25H17Cl2N3O/c1-31-19-8-7-16-13-18(6-5-17(16)14-19)24-23(15-9-11-28-12-10-15)29-25(30-24)22-20(26)3-2-4-21(22)27/h2-14H,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 17: 5514-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.052 BindingDB Entry DOI: 10.7270/Q2542N96
					More data for this Ligand-Target Pair