BDBM50221551 4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)phenylamino)benzo[e][1,2,4]triazin-7-yl)phenol::CHEMBL250623::US8481536, 512

SMILES: Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl

InChI Key: InChIKey=PDEWZRGITAXNMH-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221551 (4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)...) Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl Show InChI InChI=1S/C24H23ClN6O3S/c1-15-12-16(20-14-18(32)4-7-21(20)25)13-22-23(15)28-24(30-29-22)27-17-2-5-19(6-3-17)35(33,34)31-10-8-26-9-11-31/h2-7,12-14,26,32H,8-11H2,1H3,(H,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of Abl				Bioorg Med Chem Lett 17: 5812-8 (2007) Article DOI: 10.1016/j.bmcl.2007.08.043 BindingDB Entry DOI: 10.7270/Q2M32VGM
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221551 (4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)...) Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl Show InChI InChI=1S/C24H23ClN6O3S/c1-15-12-16(20-14-18(32)4-7-21(20)25)13-22-23(15)28-24(30-29-22)27-17-2-5-19(6-3-17)35(33,34)31-10-8-26-9-11-31/h2-7,12-14,26,32H,8-11H2,1H3,(H,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair