BDBM50221773 4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxymethyl)-2-oxy-furazan-3-carboxylic acid amide::CHEMBL243266::rac-4-(4-{(2R)-[2-(3,5-dihydroxyphenyl)-(2S)-hydroxyethylamino]propyl}phenoxymethyl)furoxan-3-carboxamide

SMILES: CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1

InChI Key: InChIKey=ATTPETUTYJEEIJ-UHFFFAOYSA-N

Data: 10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50221773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in pres...				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in prese...				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta in presence of 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta in presence of 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilating activity against phenylephrine-induced contractions in rat thoracic aorta				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilating activity against phenylephrine-induced contractions in rat thoracic aorta				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in prese...				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50221773 (4-(4-{2-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethyla...) Show SMILES CC(Cc1ccc(OCc2no[n+]([O-])c2C(N)=O)cc1)NCC(O)c1cc(O)cc(O)c1 |w:1.0,22.24| Show InChI InChI=1S/C21H24N4O7/c1-12(23-10-19(28)14-7-15(26)9-16(27)8-14)6-13-2-4-17(5-3-13)31-11-18-20(21(22)29)25(30)32-24-18/h2-5,7-9,12,19,23,26-28H,6,10-11H2,1H3,(H2,22,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in pres...				J Med Chem 50: 5003-11 (2007) Article DOI: 10.1021/jm0704595 BindingDB Entry DOI: 10.7270/Q28P61B5
					More data for this Ligand-Target Pair