BDBM50221886 (R)-6-(1-methyl-pyrrolidin-2-yl)-quinoline::CHEMBL388267

SMILES: CN1CCC[C@@H]1c1ccc2ncccc2c1

InChI Key: InChIKey=UFMVKWVVWRCTER-CQSZACIVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50221886 ((R)-6-(1-methyl-pyrrolidin-2-yl)-quinoline | CHEMB...) Show SMILES CN1CCC[C@@H]1c1ccc2ncccc2c1 Show InChI InChI=1S/C14H16N2/c1-16-9-3-5-14(16)12-6-7-13-11(10-12)4-2-8-15-13/h2,4,6-8,10,14H,3,5,9H2,1H3/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat cerebral cortex				J Med Chem 50: 4993-5002 (2007) Article DOI: 10.1021/jm070325r BindingDB Entry DOI: 10.7270/Q2FF3S34
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50221886 ((R)-6-(1-methyl-pyrrolidin-2-yl)-quinoline | CHEMB...) Show SMILES CN1CCC[C@@H]1c1ccc2ncccc2c1 Show InChI InChI=1S/C14H16N2/c1-16-9-3-5-14(16)12-6-7-13-11(10-12)4-2-8-15-13/h2,4,6-8,10,14H,3,5,9H2,1H3/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex				J Med Chem 50: 4993-5002 (2007) Article DOI: 10.1021/jm070325r BindingDB Entry DOI: 10.7270/Q2FF3S34
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50221886 ((R)-6-(1-methyl-pyrrolidin-2-yl)-quinoline | CHEMB...) Show SMILES CN1CCC[C@@H]1c1ccc2ncccc2c1 Show InChI InChI=1S/C14H16N2/c1-16-9-3-5-14(16)12-6-7-13-11(10-12)4-2-8-15-13/h2,4,6-8,10,14H,3,5,9H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [3H]alpha-bungarotoxin from alpha7 nAChR in rat cerebral cortex				J Med Chem 50: 4993-5002 (2007) Article DOI: 10.1021/jm070325r BindingDB Entry DOI: 10.7270/Q2FF3S34
					More data for this Ligand-Target Pair