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SMILES: Cc1c(NC2=NCCN2)cccc1-c1cccc(F)c1

InChI Key: InChIKey=UOQUQVMHGWHSFE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50222083 (CHEMBL90538) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(F)c1 |t:4| Show InChI InChI=1S/C16H16FN3/c1-11-14(12-4-2-5-13(17)10-12)6-3-7-15(11)20-16-18-8-9-19-16/h2-7,10H,8-9H2,1H3,(H2,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Affinity for Alpha-2 adrenergic receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50222083 (CHEMBL90538) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(F)c1 |t:4| Show InChI InChI=1S/C16H16FN3/c1-11-14(12-4-2-5-13(17)10-12)6-3-7-15(11)20-16-18-8-9-19-16/h2-7,10H,8-9H2,1H3,(H2,18,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-5-CT binding to 5-hydroxytryptamine 7 receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50222083 (CHEMBL90538) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(F)c1 |t:4| Show InChI InChI=1S/C16H16FN3/c1-11-14(12-4-2-5-13(17)10-12)6-3-7-15(11)20-16-18-8-9-19-16/h2-7,10H,8-9H2,1H3,(H2,18,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Affinity for Alpha-1 adrenergic receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair