BDBM50222090 (3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one::CHEMBL250221

SMILES: CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key: InChIKey=YIMHWIPPIFQTPY-QYQUYBGJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50222090 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H31NO3/c1-17(31)19-4-6-20(7-5-19)25-15-28(3)26(12-13-29(28)18(2)33-16-30-29)24-10-8-21-14-22(32)9-11-23(21)27(24)25/h4-7,14,16,24-26H,2,8-13,15H2,1,3H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222090 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H31NO3/c1-17(31)19-4-6-20(7-5-19)25-15-28(3)26(12-13-29(28)18(2)33-16-30-29)24-10-8-21-14-22(32)9-11-23(21)27(24)25/h4-7,14,16,24-26H,2,8-13,15H2,1,3H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair