BDBM50222157 2-amino-N-{(S)-2-benzyloxy-1-[1-(2-phenethylcarbamoyl-ethyl)-1H-tetrazol-5-yl]-ethyl}-2-methyl-propionamide::CHEMBL236513

SMILES: CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCC(=O)NCCc1ccccc1

InChI Key: InChIKey=NKTAMECGPOUCQU-OAQYLSRUSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50222157 (2-amino-N-{(S)-2-benzyloxy-1-[1-(2-phenethylcarbam...) Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCC(=O)NCCc1ccccc1 Show InChI InChI=1S/C25H33N7O3/c1-25(2,26)24(34)28-21(18-35-17-20-11-7-4-8-12-20)23-29-30-31-32(23)16-14-22(33)27-15-13-19-9-5-3-6-10-19/h3-12,21H,13-18,26H2,1-2H3,(H,27,33)(H,28,34)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Ghrelin from human GHSR1a after 1 hr				Bioorg Med Chem Lett 17: 5928-33 (2007) Article DOI: 10.1016/j.bmcl.2007.07.099 BindingDB Entry DOI: 10.7270/Q28P607D
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50222157 (2-amino-N-{(S)-2-benzyloxy-1-[1-(2-phenethylcarbam...) Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCC(=O)NCCc1ccccc1 Show InChI InChI=1S/C25H33N7O3/c1-25(2,26)24(34)28-21(18-35-17-20-11-7-4-8-12-20)23-29-30-31-32(23)16-14-22(33)27-15-13-19-9-5-3-6-10-19/h3-12,21H,13-18,26H2,1-2H3,(H,27,33)(H,28,34)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assay				Bioorg Med Chem Lett 17: 5928-33 (2007) Article DOI: 10.1016/j.bmcl.2007.07.099 BindingDB Entry DOI: 10.7270/Q28P607D
					More data for this Ligand-Target Pair