BDBM50222276 6,7-dihydroxy-4'-methoxyisoflavan::CHEMBL239247

SMILES: COc1ccc(cc1)C1COc2cc(O)c(O)cc2C1

InChI Key: InChIKey=HEMAEFVLALEJDS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-Lipoxygenase-2 (15-LOX-2) (Homo sapiens (Human))	BDBM50222276 (6,7-dihydroxy-4'-methoxyisoflavan | CHEMBL239247) Show SMILES COc1ccc(cc1)C1COc2cc(O)c(O)cc2C1 |w:8.8| Show InChI InChI=1S/C16H16O4/c1-19-13-4-2-10(3-5-13)12-6-11-7-14(17)15(18)8-16(11)20-9-12/h2-5,7-8,12,17-18H,6,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 15-hLO2				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50222276 (6,7-dihydroxy-4'-methoxyisoflavan | CHEMBL239247) Show SMILES COc1ccc(cc1)C1COc2cc(O)c(O)cc2C1 |w:8.8| Show InChI InChI=1S/C16H16O4/c1-19-13-4-2-10(3-5-13)12-6-11-7-14(17)15(18)8-16(11)20-9-12/h2-5,7-8,12,17-18H,6,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 12-hLO				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50222276 (6,7-dihydroxy-4'-methoxyisoflavan | CHEMBL239247) Show SMILES COc1ccc(cc1)C1COc2cc(O)c(O)cc2C1 |w:8.8| Show InChI InChI=1S/C16H16O4/c1-19-13-4-2-10(3-5-13)12-6-11-7-14(17)15(18)8-16(11)20-9-12/h2-5,7-8,12,17-18H,6,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 15-hLO1				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair