BDBM50222278 7,8-dihydroxyisoflavone::CHEMBL241813

SMILES: Oc1ccc2c(occ(-c3ccccc3)c2=O)c1O

InChI Key: InChIKey=HNPAPWSBQJTTPD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-Lipoxygenase-2 (15-LOX-2) (Homo sapiens (Human))	BDBM50222278 (7,8-dihydroxyisoflavone | CHEMBL241813) Show SMILES Oc1ccc2c(occ(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C15H10O4/c16-12-7-6-10-13(17)11(8-19-15(10)14(12)18)9-4-2-1-3-5-9/h1-8,16,18H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 15-hLO2				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50222278 (7,8-dihydroxyisoflavone | CHEMBL241813) Show SMILES Oc1ccc2c(occ(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C15H10O4/c16-12-7-6-10-13(17)11(8-19-15(10)14(12)18)9-4-2-1-3-5-9/h1-8,16,18H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 15-hLO1				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50222278 (7,8-dihydroxyisoflavone | CHEMBL241813) Show SMILES Oc1ccc2c(occ(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C15H10O4/c16-12-7-6-10-13(17)11(8-19-15(10)14(12)18)9-4-2-1-3-5-9/h1-8,16,18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Chile Curated by ChEMBL					Assay Description Inhibition of 12-hLO				Bioorg Med Chem 15: 7408-25 (2007) Article DOI: 10.1016/j.bmc.2007.07.036 BindingDB Entry DOI: 10.7270/Q2RN37KN
					More data for this Ligand-Target Pair