BDBM50222323 CHEMBL126274

SMILES: ONC(=O)CCCCCCc1nc(cs1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=VWBBPADKULAZAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2 (Homo sapiens (Human))	BDBM50222323 (CHEMBL126274) Show SMILES ONC(=O)CCCCCCc1nc(cs1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H24N2O2S/c25-21(24-26)10-6-1-2-7-11-22-23-20(16-27-22)19-14-12-18(13-15-19)17-8-4-3-5-9-17/h3-5,8-9,12-16,26H,1-2,6-7,10-11H2,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells				Bioorg Med Chem Lett 13: 3817-20 (2003) BindingDB Entry DOI: 10.7270/Q23F4RVV
					More data for this Ligand-Target Pair