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SMILES: ONC(=O)CCCCCCc1cnc(o1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=HLYPKXDQBACOJP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222344   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2


(Homo sapiens (Human))		BDBM50222344
PNG
(CHEMBL339796)
Show SMILES ONC(=O)CCCCCCc1cnc(o1)-c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C22H24N2O3/c25-21(24-26)11-7-2-1-6-10-20-16-23-22(27-20)19-14-12-18(13-15-19)17-8-4-3-5-9-17/h3-5,8-9,12-16,26H,1-2,6-7,10-11H2,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 12n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells

Bioorg Med Chem Lett 13: 3817-20 (2003)


BindingDB Entry DOI: 10.7270/Q23F4RVV
More data for this
Ligand-Target Pair