BDBM50222435 6,7-dimethoxy-4-(4-phenylbut-1-ynyl)quinazoline::CHEMBL250318
SMILES: COc1cc2ncnc(C#CCCc3ccccc3)c2cc1OC
InChI Key: InChIKey=UJTHKWFURJCQDD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50222435 (6,7-dimethoxy-4-(4-phenylbut-1-ynyl)quinazoline | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of partially purified EGFR tyrosine kinase from human A431 cells | Bioorg Med Chem Lett 17: 5863-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.020 BindingDB Entry DOI: 10.7270/Q2H70FJ7 | |||||||||||
More data for this Ligand-Target Pair |