BDBM50222435 6,7-dimethoxy-4-(4-phenylbut-1-ynyl)quinazoline::CHEMBL250318

SMILES: COc1cc2ncnc(C#CCCc3ccccc3)c2cc1OC

InChI Key: InChIKey=UJTHKWFURJCQDD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50222435 (6,7-dimethoxy-4-(4-phenylbut-1-ynyl)quinazoline | ...) Show SMILES COc1cc2ncnc(C#CCCc3ccccc3)c2cc1OC Show InChI InChI=1S/C20H18N2O2/c1-23-19-12-16-17(21-14-22-18(16)13-20(19)24-2)11-7-6-10-15-8-4-3-5-9-15/h3-5,8-9,12-14H,6,10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of partially purified EGFR tyrosine kinase from human A431 cells				Bioorg Med Chem Lett 17: 5863-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.020 BindingDB Entry DOI: 10.7270/Q2H70FJ7
					More data for this Ligand-Target Pair