BDBM50222510 CHEMBL249194::N-(3-phenoxyphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide
SMILES: O=C(Nc1cccc(Oc2ccccc2)c1)c1cccnc1NCc1ccncc1
InChI Key: InChIKey=NNDHTJMIFWLTJW-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50222510 (CHEMBL249194 | N-(3-phenoxyphenyl)-2-(pyridin-4-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Inhibition of phosphorylated-Kdr after 30 mins | Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N | |||||||||||
More data for this Ligand-Target Pair |