BDBM50222519 CHEMBL250665::N-(4-chlorophenyl)-4-(pyridin-4-ylmethylamino)pyrimidine-5-carboxamide

SMILES: Clc1ccc(NC(=O)c2cncnc2NCc2ccncc2)cc1

InChI Key: InChIKey=AASKJKFOWFARIP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222519 (CHEMBL250665 | N-(4-chlorophenyl)-4-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)c2cncnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C17H14ClN5O/c18-13-1-3-14(4-2-13)23-17(24)15-10-20-11-22-16(15)21-9-12-5-7-19-8-6-12/h1-8,10-11H,9H2,(H,23,24)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair