BDBM50222520 CHEMBL248980::N-(3-ethylphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide

SMILES: CCc1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1

InChI Key: InChIKey=VPSIZGXQXQGXAD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222520 (CHEMBL248980 | N-(3-ethylphenyl)-2-(pyridin-4-ylme...) Show SMILES CCc1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H20N4O/c1-2-15-5-3-6-17(13-15)24-20(25)18-7-4-10-22-19(18)23-14-16-8-11-21-12-9-16/h3-13H,2,14H2,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair