BDBM50222523 5-bromo-N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)nicotinamide::CHEMBL250471

SMILES: Clc1ccc(NC(=O)c2cc(Br)cnc2NCc2ccncc2)cc1

InChI Key: InChIKey=GPFCIUJVYMETBL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222523 (5-bromo-N-(4-chlorophenyl)-2-(pyridin-4-ylmethylam...) Show SMILES Clc1ccc(NC(=O)c2cc(Br)cnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C18H14BrClN4O/c19-13-9-16(18(25)24-15-3-1-14(20)2-4-15)17(23-11-13)22-10-12-5-7-21-8-6-12/h1-9,11H,10H2,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair