Found 4 hits for monomerid = 50222788 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222788
(1-(2-cyclopentyl-7-(4-methylpiperidine-1-carbonyl)...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(C(C)=O)c3CN(Cc3c2c1)C1CCCC1 Show InChI InChI=1S/C24H31N3O2/c1-16-9-11-25(12-10-16)24(29)18-7-8-22-20(13-18)21-14-26(19-5-3-4-6-19)15-23(21)27(22)17(2)28/h7-8,13,16,19H,3-6,9-12,14-15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 88.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montreal
Curated by ChEMBL
| Assay Description Binding affinity to human CB2 receptor |
Bioorg Med Chem Lett 17: 6183-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.019 BindingDB Entry DOI: 10.7270/Q2TH8MD3 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222788
(1-(2-cyclopentyl-7-(4-methylpiperidine-1-carbonyl)...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(C(C)=O)c3CN(Cc3c2c1)C1CCCC1 Show InChI InChI=1S/C24H31N3O2/c1-16-9-11-25(12-10-16)24(29)18-7-8-22-20(13-18)21-14-26(19-5-3-4-6-19)15-23(21)27(22)17(2)28/h7-8,13,16,19H,3-6,9-12,14-15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 88.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor |
J Med Chem 52: 369-78 (2009)
Article DOI: 10.1021/jm801044g BindingDB Entry DOI: 10.7270/Q2VQ33M2 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222788
(1-(2-cyclopentyl-7-(4-methylpiperidine-1-carbonyl)...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(C(C)=O)c3CN(Cc3c2c1)C1CCCC1 Show InChI InChI=1S/C24H31N3O2/c1-16-9-11-25(12-10-16)24(29)18-7-8-22-20(13-18)21-14-26(19-5-3-4-6-19)15-23(21)27(22)17(2)28/h7-8,13,16,19H,3-6,9-12,14-15H2,1-2H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor |
J Med Chem 52: 369-78 (2009)
Article DOI: 10.1021/jm801044g BindingDB Entry DOI: 10.7270/Q2VQ33M2 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222788
(1-(2-cyclopentyl-7-(4-methylpiperidine-1-carbonyl)...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(C(C)=O)c3CN(Cc3c2c1)C1CCCC1 Show InChI InChI=1S/C24H31N3O2/c1-16-9-11-25(12-10-16)24(29)18-7-8-22-20(13-18)21-14-26(19-5-3-4-6-19)15-23(21)27(22)17(2)28/h7-8,13,16,19H,3-6,9-12,14-15H2,1-2H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montreal
Curated by ChEMBL
| Assay Description Binding affinity to human CB1 receptor |
Bioorg Med Chem Lett 17: 6183-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.019 BindingDB Entry DOI: 10.7270/Q2TH8MD3 |
More data for this Ligand-Target Pair | |