Found 3 hits for monomerid = 50222810 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222810
((2-cyclopentyl-4-(phenylsulfonyl)-1,2,3,4-tetrahyd...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(c3CN(Cc3c2c1)C1CCCC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H33N3O3S/c1-20-13-15-29(16-14-20)28(32)21-11-12-26-24(17-21)25-18-30(22-7-5-6-8-22)19-27(25)31(26)35(33,34)23-9-3-2-4-10-23/h2-4,9-12,17,20,22H,5-8,13-16,18-19H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montreal
Curated by ChEMBL
| Assay Description Binding affinity to human CB2 receptor |
Bioorg Med Chem Lett 17: 6183-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.019 BindingDB Entry DOI: 10.7270/Q2TH8MD3 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222810
((2-cyclopentyl-4-(phenylsulfonyl)-1,2,3,4-tetrahyd...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(c3CN(Cc3c2c1)C1CCCC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H33N3O3S/c1-20-13-15-29(16-14-20)28(32)21-11-12-26-24(17-21)25-18-30(22-7-5-6-8-22)19-27(25)31(26)35(33,34)23-9-3-2-4-10-23/h2-4,9-12,17,20,22H,5-8,13-16,18-19H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montreal
Curated by ChEMBL
| Assay Description Binding affinity to human CB1 receptor |
Bioorg Med Chem Lett 17: 6183-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.019 BindingDB Entry DOI: 10.7270/Q2TH8MD3 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222810
((2-cyclopentyl-4-(phenylsulfonyl)-1,2,3,4-tetrahyd...)Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(c3CN(Cc3c2c1)C1CCCC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H33N3O3S/c1-20-13-15-29(16-14-20)28(32)21-11-12-26-24(17-21)25-18-30(22-7-5-6-8-22)19-27(25)31(26)35(33,34)23-9-3-2-4-10-23/h2-4,9-12,17,20,22H,5-8,13-16,18-19H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 15.6 | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montreal
Curated by ChEMBL
| Assay Description Agonist activity at human CB2 receptor by GTPgamma[35S] assay |
Bioorg Med Chem Lett 17: 6183-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.019 BindingDB Entry DOI: 10.7270/Q2TH8MD3 |
More data for this Ligand-Target Pair | |