BDBM50222830 CHEMBL248014::N-(5-tert-butyl-3-(2-methoxyethyl)-4-methylthiazol-2(3H)-ylidene)-3-(trifluoromethyl)benzamide

SMILES: COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C

InChI Key: InChIKey=WOOLJWGVJCDMEU-QJOMJCCJSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50222830 (CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...) Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50222830 (CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...) Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50222830 (CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...) Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay				Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ
					More data for this Ligand-Target Pair