BDBM50222841 (Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthiazol-2(3H)-ylidene)benzamide::CHEMBL247996
SMILES: Cc1c(s\c(=N/C(=O)c2cccc(Br)c2)n1CC1CC1)C(C)(C)C
InChI Key: InChIKey=NGBMQCUWIZPJCG-UZYVYHOESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50222841 ((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50222841 ((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay | Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50222841 ((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 6299-304 (2007) Article DOI: 10.1016/j.bmcl.2007.09.004 BindingDB Entry DOI: 10.7270/Q2PG1SJQ | |||||||||||
More data for this Ligand-Target Pair |