BindingDB logo
myBDB logout

BDBM50222857 6-(4-chlorophenyl)-2-(2-methylphenyl)-3-{[1-(3,3,3-trifluoropropyl)piperidin-3-yl]methyl}quinazolin-4(3H)-one::CHEMBL390648

SMILES: Cc1ccccc1-c1nc2ccc(cc2c(=O)n1CC1CCCN(CCC(F)(F)F)C1)-c1ccc(Cl)cc1

InChI Key: InChIKey=MNVDKXPJRHTVKG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222857   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Ovis aries)		BDBM50222857
PNG
(6-(4-chlorophenyl)-2-(2-methylphenyl)-3-{[1-(3,3,3...)
Show SMILES Cc1ccccc1-c1nc2ccc(cc2c(=O)n1CC1CCCN(CCC(F)(F)F)C1)-c1ccc(Cl)cc1 |w:19.21|
Show InChI InChI=1S/C30H29ClF3N3O/c1-20-5-2-3-7-25(20)28-35-27-13-10-23(22-8-11-24(31)12-9-22)17-26(27)29(38)37(28)19-21-6-4-15-36(18-21)16-14-30(32,33)34/h2-3,5,7-13,17,21H,4,6,14-16,18-19H2,1H3
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 250n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay

J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair