new BindingDB logo
myBDB logout

BDBM50222860 6-(2-chlorophenyl)-2-isopropyl-3-(((S)-1-isopropylpiperidin-3-yl)methyl)quinazolin-4(3H)-one::CHEMBL244882

SMILES: CC(C)N1CCC[C@H](Cn2c(nc3ccc(cc3c2=O)-c2ccccc2Cl)C(C)C)C1

InChI Key: InChIKey=CRUHNOUIHGMRQX-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222860   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Ovis aries)
BDBM50222860
PNG
(6-(2-chlorophenyl)-2-isopropyl-3-(((S)-1-isopropyl...)
Show SMILES CC(C)N1CCC[C@H](Cn2c(nc3ccc(cc3c2=O)-c2ccccc2Cl)C(C)C)C1
Show InChI InChI=1S/C26H32ClN3O/c1-17(2)25-28-24-12-11-20(21-9-5-6-10-23(21)27)14-22(24)26(31)30(25)16-19-8-7-13-29(15-19)18(3)4/h5-6,9-12,14,17-19H,7-8,13,15-16H2,1-4H3/t19-/m0/s1
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
127n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay


J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair