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BDBM50222877 6-(4-chlorophenyl)-3-[(4-isopropylmorpholin-2-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one::CHEMBL440952

SMILES: CC(C)N1CCOC(Cn2c(nc3ccc(cc3c2=O)-c2ccc(Cl)cc2)-c2ccccc2C)C1

InChI Key: InChIKey=AWXHNHYIKOYDPD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222877   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Ovis aries)
BDBM50222877
PNG
(6-(4-chlorophenyl)-3-[(4-isopropylmorpholin-2-yl)m...)
Show SMILES CC(C)N1CCOC(Cn2c(nc3ccc(cc3c2=O)-c2ccc(Cl)cc2)-c2ccccc2C)C1 |w:7.7|
Show InChI InChI=1S/C29H30ClN3O2/c1-19(2)32-14-15-35-24(17-32)18-33-28(25-7-5-4-6-20(25)3)31-27-13-10-22(16-26(27)29(33)34)21-8-11-23(30)12-9-21/h4-13,16,19,24H,14-15,17-18H2,1-3H3
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
190n/an/an/an/an/an/an/an/a



Bayer Pharmaceuticals Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay


J Med Chem 50: 5202-16 (2007)


Article DOI: 10.1021/jm070071+
BindingDB Entry DOI: 10.7270/Q2WH2QT2
More data for this
Ligand-Target Pair