BDBM50222977 CHEMBL250815::N-((1R,2S)-2-(cyclopentyloxy)-2,3-dihydro-1H-inden-1-yl)-3,6-diethyl-5-(4-methylpyridin-2-yloxy)pyrazin-2-amine

SMILES: CCc1nc(Oc2cc(C)ccn2)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OC1CCCC1

InChI Key: InChIKey=NJISJKWUAGTCPC-AZGAKELHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50222977 (CHEMBL250815 | N-((1R,2S)-2-(cyclopentyloxy)-2,3-d...) Show SMILES CCc1nc(Oc2cc(C)ccn2)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OC1CCCC1 Show InChI InChI=1S/C28H34N4O2/c1-4-22-27(30-23(5-2)28(31-22)34-25-16-18(3)14-15-29-25)32-26-21-13-9-6-10-19(21)17-24(26)33-20-11-7-8-12-20/h6,9-10,13-16,20,24,26H,4-5,7-8,11-12,17H2,1-3H3,(H,30,32)/t24-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cells				Bioorg Med Chem Lett 17: 6250-6 (2007) Article DOI: 10.1016/j.bmcl.2007.09.008 BindingDB Entry DOI: 10.7270/Q2F76C8G
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