BDBM50223017 2-((1R,2S)-1-(3,6-diethyl-5-(4-methylpyridin-2-yloxy)pyrazin-2-ylamino)-2,3-dihydro-1H-inden-2-yloxy)ethanol::CHEMBL400082

SMILES: CCc1nc(Oc2cc(C)ccn2)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCO

InChI Key: InChIKey=GCBNYKFTHPFEKE-JTHBVZDNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50223017 (2-((1R,2S)-1-(3,6-diethyl-5-(4-methylpyridin-2-ylo...) Show SMILES CCc1nc(Oc2cc(C)ccn2)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCO Show InChI InChI=1S/C25H30N4O3/c1-4-19-24(27-20(5-2)25(28-19)32-22-14-16(3)10-11-26-22)29-23-18-9-7-6-8-17(18)15-21(23)31-13-12-30/h6-11,14,21,23,30H,4-5,12-13,15H2,1-3H3,(H,27,29)/t21-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cells				Bioorg Med Chem Lett 17: 6250-6 (2007) Article DOI: 10.1016/j.bmcl.2007.09.008 BindingDB Entry DOI: 10.7270/Q2F76C8G
					More data for this Ligand-Target Pair