BDBM50223027 CHEMBL430019::N-((1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethyl-5-(6-methylpyridin-2-yloxy)pyrazin-2-amine

SMILES: CCO[C@H]1Cc2ccccc2[C@H]1Nc1nc(CC)c(Oc2cccc(C)n2)nc1CC

InChI Key: InChIKey=HZDVPISTKNEOJS-JTHBVZDNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50223027 (CHEMBL430019 | N-((1R,2S)-2-ethoxy-2,3-dihydro-1H-...) Show SMILES CCO[C@H]1Cc2ccccc2[C@H]1Nc1nc(CC)c(Oc2cccc(C)n2)nc1CC Show InChI InChI=1S/C25H30N4O2/c1-5-19-24(29-23-18-13-9-8-12-17(18)15-21(23)30-7-3)27-20(6-2)25(28-19)31-22-14-10-11-16(4)26-22/h8-14,21,23H,5-7,15H2,1-4H3,(H,27,29)/t21-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	472	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cells				Bioorg Med Chem Lett 17: 6250-6 (2007) Article DOI: 10.1016/j.bmcl.2007.09.008 BindingDB Entry DOI: 10.7270/Q2F76C8G
					More data for this Ligand-Target Pair