BDBM50223174 2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-one oxalate::CHEMBL398043

SMILES: O=C1CCON1CC#CC[NH+]1CCCCC1

InChI Key: InChIKey=RXJJLNUPBMTGAW-UHFFFAOYSA-O

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50223174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50223174 (2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CC[NH+]1CCCCC1 Show InChI InChI=1S/C12H18N2O2/c15-12-6-11-16-14(12)10-5-4-9-13-7-2-1-3-8-13/h1-3,6-11H2/p+1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50223174 (2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CC[NH+]1CCCCC1 Show InChI InChI=1S/C12H18N2O2/c15-12-6-11-16-14(12)10-5-4-9-13-7-2-1-3-8-13/h1-3,6-11H2/p+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50223174 (2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CC[NH+]1CCCCC1 Show InChI InChI=1S/C12H18N2O2/c15-12-6-11-16-14(12)10-5-4-9-13-7-2-1-3-8-13/h1-3,6-11H2/p+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	544	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M5 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50223174 (2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CC[NH+]1CCCCC1 Show InChI InChI=1S/C12H18N2O2/c15-12-6-11-16-14(12)10-5-4-9-13-7-2-1-3-8-13/h1-3,6-11H2/p+1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	792	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M4 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50223174 (2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CC[NH+]1CCCCC1 Show InChI InChI=1S/C12H18N2O2/c15-12-6-11-16-14(12)10-5-4-9-13-7-2-1-3-8-13/h1-3,6-11H2/p+1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	819	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M1 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair