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SMILES: COc1ccc(cc1OC1CCC1)C1(CCN(CC(=O)NO)CC1)C#N

InChI Key: InChIKey=JTSJSXZAIAWVFR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223263   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50223263
PNG
(CHEMBL291889)
Show SMILES COc1ccc(cc1OC1CCC1)C1(CCN(CC(=O)NO)CC1)C#N
Show InChI InChI=1S/C19H25N3O4/c1-25-16-6-5-14(11-17(16)26-15-3-2-4-15)19(13-20)7-9-22(10-8-19)12-18(23)21-24/h5-6,11,15,24H,2-4,7-10,12H2,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 0.180n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells

Bioorg Med Chem Lett 14: 207-10 (2004)


BindingDB Entry DOI: 10.7270/Q21G0PFV
More data for this
Ligand-Target Pair