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SMILES: CCOc1ccc(cc1OC1CCCC1)C1(CCN(CC(=O)NO)CC1)C#N

InChI Key: InChIKey=XHHHLXUOGDNSNR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223271   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50223271
PNG
(CHEMBL63028)
Show SMILES CCOc1ccc(cc1OC1CCCC1)C1(CCN(CC(=O)NO)CC1)C#N
Show InChI InChI=1S/C21H29N3O4/c1-2-27-18-8-7-16(13-19(18)28-17-5-3-4-6-17)21(15-22)9-11-24(12-10-21)14-20(25)23-26/h7-8,13,17,26H,2-6,9-12,14H2,1H3,(H,23,25)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 6.20n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells

Bioorg Med Chem Lett 14: 207-10 (2004)


BindingDB Entry DOI: 10.7270/Q21G0PFV
More data for this
Ligand-Target Pair