BDBM50223366 1-((4-phenyl-1H-imidazol-2-yl)methyl)-3-(4-phenylthiazol-2-yl)urea::CHEMBL393210

SMILES: O=C(NCc1nc(c[nH]1)-c1ccccc1)Nc1nc(cs1)-c1ccccc1

InChI Key: InChIKey=VVVIVRROAZHDAR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabK) (Streptococcus pneumoniae)	BDBM50223366 (1-((4-phenyl-1H-imidazol-2-yl)methyl)-3-(4-phenylt...) Show SMILES O=C(NCc1nc(c[nH]1)-c1ccccc1)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H17N5OS/c26-19(25-20-24-17(13-27-20)15-9-5-2-6-10-15)22-12-18-21-11-16(23-18)14-7-3-1-4-8-14/h1-11,13H,12H2,(H,21,23)(H2,22,24,25,26)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae enoyl-ACP reductase FabK				Bioorg Med Chem 15: 7325-36 (2007) Article DOI: 10.1016/j.bmc.2007.08.050 BindingDB Entry DOI: 10.7270/Q25T3MBH
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabI) (Escherichia coli)	BDBM50223366 (1-((4-phenyl-1H-imidazol-2-yl)methyl)-3-(4-phenylt...) Show SMILES O=C(NCc1nc(c[nH]1)-c1ccccc1)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H17N5OS/c26-19(25-20-24-17(13-27-20)15-9-5-2-6-10-15)22-12-18-21-11-16(23-18)14-7-3-1-4-8-14/h1-11,13H,12H2,(H,21,23)(H2,22,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of Escherichia coli enoyl-ACP reductase FabI				Bioorg Med Chem 15: 7325-36 (2007) Article DOI: 10.1016/j.bmc.2007.08.050 BindingDB Entry DOI: 10.7270/Q25T3MBH
					More data for this Ligand-Target Pair