BDBM50223410 CHEMBL82931

SMILES: COc1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C(/C)\C=C\C(=O)NO)cc1

InChI Key: InChIKey=LQVOPOOSNCJYEY-YQIFXAOGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50223410 (CHEMBL82931) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C(/C)\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C19H20N2O5S/c1-14(3-12-19(22)20-23)13-15-4-6-16(7-5-15)21-27(24,25)18-10-8-17(26-2)9-11-18/h3-13,21,23H,1-2H3,(H,20,22)/b12-3+,14-13+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extract				Bioorg Med Chem Lett 14: 2477-81 (2004) BindingDB Entry DOI: 10.7270/Q2S184Q6
					More data for this Ligand-Target Pair