BDBM50223415 CHEMBL312253

SMILES: C\C(\C=C\C(O)=O)=C/c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=HIUIHMARBRKSSO-HUYCJKDXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50223415 (CHEMBL312253) Show SMILES C\C(\C=C\C(O)=O)=C/c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H16ClNO4S/c1-13(2-11-18(21)22)12-14-3-7-16(8-4-14)20-25(23,24)17-9-5-15(19)6-10-17/h2-12,20H,1H3,(H,21,22)/b11-2+,13-12+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extract				Bioorg Med Chem Lett 14: 2477-81 (2004) BindingDB Entry DOI: 10.7270/Q2S184Q6
					More data for this Ligand-Target Pair