BDBM50223432 CHEMBL235612::N-(2,6-difluorobenzyl)-5-((R)-2-((R)-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)propyl)-1H-indole-2-carboxamide

SMILES: C[C@H](Cc1ccc2[nH]c(cc2c1)C(=O)NCc1c(F)cccc1F)NC[C@H](O)c1ccc(O)c(CO)c1

InChI Key: InChIKey=VOHPKWTZPSIPKC-JWIGPWBQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50223432 (CHEMBL235612 | N-(2,6-difluorobenzyl)-5-((R)-2-((R...) Show SMILES C[C@H](Cc1ccc2[nH]c(cc2c1)C(=O)NCc1c(F)cccc1F)NC[C@H](O)c1ccc(O)c(CO)c1 Show InChI InChI=1S/C28H29F2N3O4/c1-16(31-14-27(36)18-6-8-26(35)20(11-18)15-34)9-17-5-7-24-19(10-17)12-25(33-24)28(37)32-13-21-22(29)3-2-4-23(21)30/h2-8,10-12,16,27,31,33-36H,9,13-15H2,1H3,(H,32,37)/t16-,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0530	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levels				Bioorg Med Chem Lett 17: 6188-91 (2007) Article DOI: 10.1016/j.bmcl.2007.09.031 BindingDB Entry DOI: 10.7270/Q2222VM3
					More data for this Ligand-Target Pair