BDBM50223438 CHEMBL238347::N-(2,6-dimethoxybenzyl)-1-benzyl-5-((R)-2-((R)-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)propyl)-1H-indole-2-carboxamide

SMILES: COc1cccc(OC)c1CNC(=O)c1cc2cc(C[C@@H](C)NC[C@H](O)c3ccc(O)c(CO)c3)ccc2n1Cc1ccccc1

InChI Key: InChIKey=NRNNWQIWZUUFQS-ZWVRTZEQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50223438 (CHEMBL238347 | N-(2,6-dimethoxybenzyl)-1-benzyl-5-...) Show SMILES COc1cccc(OC)c1CNC(=O)c1cc2cc(C[C@@H](C)NC[C@H](O)c3ccc(O)c(CO)c3)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C37H41N3O6/c1-24(38-21-34(43)27-13-15-33(42)29(18-27)23-41)16-26-12-14-31-28(17-26)19-32(40(31)22-25-8-5-4-6-9-25)37(44)39-20-30-35(45-2)10-7-11-36(30)46-3/h4-15,17-19,24,34,38,41-43H,16,20-23H2,1-3H3,(H,39,44)/t24-,34+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.687	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levels				Bioorg Med Chem Lett 17: 6188-91 (2007) Article DOI: 10.1016/j.bmcl.2007.09.031 BindingDB Entry DOI: 10.7270/Q2222VM3
					More data for this Ligand-Target Pair