BDBM50223444 CHEMBL236042::N-(3-methoxyphenethyl)-5-((R)-2-((R)-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)propyl)-1H-indole-2-carboxamide

SMILES: COc1cccc(CCNC(=O)c2cc3cc(C[C@@H](C)NC[C@H](O)c4ccc(O)c(CO)c4)ccc3[nH]2)c1

InChI Key: InChIKey=FDAKLYKEIOPOKK-XBBWARJSSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50223444 (CHEMBL236042 | N-(3-methoxyphenethyl)-5-((R)-2-((R...) Show SMILES COc1cccc(CCNC(=O)c2cc3cc(C[C@@H](C)NC[C@H](O)c4ccc(O)c(CO)c4)ccc3[nH]2)c1 Show InChI InChI=1S/C30H35N3O5/c1-19(32-17-29(36)22-7-9-28(35)24(15-22)18-34)12-21-6-8-26-23(13-21)16-27(33-26)30(37)31-11-10-20-4-3-5-25(14-20)38-2/h3-9,13-16,19,29,32-36H,10-12,17-18H2,1-2H3,(H,31,37)/t19-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.254	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levels				Bioorg Med Chem Lett 17: 6188-91 (2007) Article DOI: 10.1016/j.bmcl.2007.09.031 BindingDB Entry DOI: 10.7270/Q2222VM3
					More data for this Ligand-Target Pair